The US president-elect released a short video about his plans for his administration, which included the intention to quit the Trans-Pacific Partnership (TPP).
“I am going to issue a notification of intent to withdraw from the Trans-Pacific Partnership, a potential disaster for our country,” Mr Trump said.
“Instead, we will negotiate fair, bilateral trade deals that bring jobs and industry back onto American shores.”
Mr Trump said in the video he is assembling a Cabinet made up of “patriots” and that his agenda “will be based on a simple core principle – putting America first”.
He repeated a number of his promises for the first 100 days of his administration, including vows to negotiate new trade deals, remove regulations on businesses and establish a five-year ban on executive officials becoming lobbyists.
Notably missing from his promises is his pledge to repeal the Affordable Care Act and his vow to build a southern border wall with Mexico.
The president-elect later appeared to deny that he is using the powers of his future office to benefit his businesses worldwide.
He tweeted: “Prior to the election it was well known that I have interests in properties all over the world.
Only the crooked media makes this a big deal!”Mr Trump has said repeatedly that he will leave his company to his children and have no interest in it – but three of his adult children are also playing key roles in his transition.
The tweet came after the tycoon spent the day at Trump Tower meeting almost a dozen people who could take jobs in his administration, although he did not announce any appointments.